%% Searchlight analysis in the volume
%
% This analysis is quite bare-bones - data is simulated to come directly
% from load_nii rather than through fmri_dataset, and voxel indices in each
% searchlight are computed directly in this script rather than using
% a helper function such as spherical_voxel_selection.
%
% Note: for running searchlights it is recommended to use
% cosmo_searchlight and cosmo_spherical_neighborhood
%
% # For CoSMoMVPA's copyright information and license terms, #
% # see the COPYING file distributed with CoSMoMVPA. #
%% Define input files and searchlight radius
radius = 3; % in voxel units
config = cosmo_config();
data_path = fullfile(config.tutorial_data_path, 'ak6', 's01');
half1_fn = fullfile(data_path, 'glm_T_stats_odd.nii');
half2_fn = fullfile(data_path, 'glm_T_stats_even.nii');
mask_fn = fullfile(data_path, 'brain_mask.nii');
%% Load the data and extract the data in the mask
ni_samples1 = load_nii(half1_fn);
ni_samples2 = load_nii(half2_fn);
ni_mask = load_nii(mask_fn);
% Get the volume data
half1_samples = ni_samples1.img;
half2_samples = ni_samples2.img;
mask = ni_mask.img;
% combine the two halves, and define the masks
samples = cat(4, half1_samples, half2_samples);
nsamples = size(samples, 4); % should be 6
half1_samples_mask = (1:nsamples) <= nsamples / 2;
half2_samples_mask = ~half1_samples_mask;
%% Searchlight data 'contrast' definition
% Define how correlations values are going to be weighted
% mean zero, positive on diagonal, negative elsewhere.
% Note that this matrix has a mean of zero, so under the null hypothesis
% that correlations are equal on and off the diagonal, weighting these
% correlations by the contrast matrix and then summing them should
% give a mean of zero as well.
contrast_matrix = eye(6) - 1 / 6;
%% Define voxel offset positions in the searchlight
% get the sphere offsets
sphere_offsets = cosmo_sphere_offsets(radius);
noffsets = size(sphere_offsets, 1);
%% Prepare for output
% allocate space for data in searchlight once, then overwrite in for-loop below
sphere_data = zeros(nsamples, noffsets);
voldim = size(mask);
output = zeros(voldim);
visited = false(voldim);
%% Run the searchlight
% for pretty progress reporting
prev_msg = '';
clock_start = clock();
% run over voxels in all three spatial dimensions
for ii = 1:voldim(1)
for jj = 1:voldim(2)
for kk = 1:voldim(3)
% if outside the mask, continue with next voxel
%%%% >>> Your code here <<< %%%%
% fill up the sphere_data matrix with data from the sphere
% centered around location (ii, jj, kk).
% for every valid position increment row_pos first, then
% fill it with the sample data for of that position.
% (a valid position p=[i, j, k] has 1 <= p(m) <= voldim(m) for
% m=1, 2 and 3, and is not outside the mask).
row_pos = 0;
sphere_data(:) = NaN; % not necessary, but used to check validity of data
%%%% >>> Your code here <<< %%%%
% get data only as far down as we got voxels.
selected_sphere_data = sphere_data(:, 1:row_pos);
% a little sanity check
if any(isnan(selected_sphere_data))
error('found NaN - this should not happen');
end
% take the data from the two halves using the
% half_{1,2}samples_mask
%%%% >>> Your code here <<< %%%%
% Compute correlations, fisher transform, then weigh them.
% Store the sum of the weighted transformed correlations in the
% 'output' array.
%
% Use cosmo_corr instead of corr for faster computations
%%%% >>> Your code here <<< %%%%
% set this voxel as visited
visited(ii, jj, kk) = true;
end
end
% Keep us updated on progress
msg = sprintf('%d slices: mean %.3f', ii, mean(output(visited)));
prev_msg = cosmo_show_progress(clock_start, ii / voldim(1), msg, prev_msg);
end
%% Save the results
ni_output = ni_samples1;
ni_output.img = output;
ni_output.hdr.dime.dim(5) = 1;
% use the following lines to store the output as a NIFTI file
% >> save_nii(ni_output,fullfile(data_path,'sphere_offsets_searchlight.nii'));
%% Plot the results as axial slices
nslices = voldim(3);
nrows = floor(.8 * sqrt(nslices));
ncols = ceil(nslices / nrows);
output_range = [-1 1] * 2;
for k = 1:nslices
subplot(nrows, ncols, k);
% orient with top side anterior
imagesc(output(:, end:-1:1, k)', output_range);
title(sprintf('slice %d', k));
axis off;
end